When I was on a peer-review site, I often looked for the point at which I as reader was drawn into the story. I noticed that a number of scripts didn't get to the point until around half-way through the story (typically around page 45-50). From my point of view, none of these scripts benefited from such a delay.

Now certainly there may be a well-told story that takes more time than the 1/4 mark (end of Act 1) before it specifies the main conflict that the protagonist faces. But (again, in my limited experience) this strategy in these not-particularly-involving stories resulted in a lack of audience involvement with the protagonist's quest.

I'm not a big fan of rigid paradigms and beat sheets, but I think that if a story takes longer than the 1/4 point to hook the audience into the protag's quest, it had better have a darn good reason for doing so. And the audience had probably better not be conscious of this reason.