There are lots of interesting ramifications to her questions. I don't know if she intended to evoke further investigation, but that's not the point.
If a boy of the same age were to ask the same questions while combing his hair, it's unlikely there would have been such a flurry of criticism.
If a 6 year-old girl had asked the same questions while watching a cartoon, I doubt she would have been lambasted as stupid.
I haven't seen the responses from tiktok, but I would guess most of those deriding Math Girl were men.
Make-up is associated with being physically alluring, and once a young woman is looked at sexually by men, any intellectual endeavor on her part may be seen as a threat. Her intelligence has to be questioned so that she can become an object of desire, not a subject capable of independent thought. You can't be smart and pretty if you're a young woman.
Think about the biases implicit in our language.
Disparaging labels for young women: ditz, dumb blonde, bimbo, airhead....
Disparaging labels for young men: dork, geek, nerd.... Even "jock" / "dumb jock," which connotes lack of intelligence confers physical prowess. Negative terms for young women focus on emptiness and lack of significant traits.