I understand the attraction of using established pharmaceutical remedies to fight inflammation. But there seems to be a logical problem in using pharmaceuticals as the sole response.

If the immune systems of elderly people are compromised (abnormally heightened) so that they overreact in a cytokine storm, then when you apply the typical anti-inflammatory drug, you are quelling the storm but ignoring the cause of the storm. It's a little like taking a cigarette lighter out of the hand of a pyromaniac. He's just going to buy another.

Why do we not also emphasize the role of adaptogens in strengthening the immune system and making it less likely for the fire to get out of hand in the first place? There are peer-reviewed studies of the immune system strengthening capabilities of Withania somnifera (ashwaganda), for example, and there are many other adaptogens.

I noticed that the senolytic candidate in the link you provided was Dasatinib plus Quercetin; quercetin is a naturally occurring bioflavonoid (common in red onions, for example).

I'm not saying we should abandon conventional pharmaceuticals, but I believe we should support and encourage scientific evaluation of strategies that maintain or rejuvenate aging systems. Unfortunately, integrative medicine is still a niche specialty, at least in the west.

If your grandfather keeps slipping in the tub, the optimal solution is not sutures but a non-slip tub mat, and maybe some exercise.